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Epileptic Focus and Alteration of Metabolism
- 1.0432148 - FGÚ 2015 RIV US eng J - Journal Article
Otáhal, Jakub - Folbergrová, Jaroslava - Kovacs, R. - Kunz, W.S. - Maggio, N.
Epileptic Focus and Alteration of Metabolism.
International Review of Neurobiology. Roč. 114, č. 2014 (2014), s. 209-243. ISSN 0074-7742. E-ISSN 2162-5514
R&D Projects: GA ČR(CZ) GAP303/10/0999; GA ČR(CZ) GA309/05/2015; GA ČR(CZ) GA309/08/0292; GA ČR(CZ) GAP302/10/0971; GA MŠMT(CZ) LL1204; GA MZd(CZ) NT14489; GA ČR(CZ) GA14-02634S
Institutional research plan: CEZ:AV0Z50110509
Institutional support: RVO:67985823
Keywords : epilepsy * epileptogenesis * cerebral blood flow * blood brain barrier * reactive oxygen species * energy metabolism * mitochondria * oxidative posttranslational modifications * mtDNA mutations * pharmacoresistance
Subject RIV: FH - Neurology
Impact factor: 1.921, year: 2014
Some of the important issues concerning vascular and metabolic changes in pathophysiology of epilepsy are addressed. Efficient regulatory mechanisms operating in concert at several levels are discussed. It has been proposed that the substances with antioxidant properties combined with conventional therapies might provide a beneficial effect in the treatment of epilepsy
Permanent Link: http://hdl.handle.net/11104/0236614
Number of the records: 1