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Human Masseter Muscle Fibers From the Elderly Express Less Neonatal Myosin Than Those of Young Adults
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SYSNO ASEP 0380119 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve WOS Title Human Masseter Muscle Fibers From the Elderly Express Less Neonatal Myosin Than Those of Young Adults Author(s) Cvetko, E. (SI)
Karen, Petr (FGU-C)
Janáček, Jiří (FGU-C) RID, ORCID
Kubínová, Lucie (FGU-C) RID, ORCID
Plasencia, A.L. (ES)
Eržen, I. (SI)Source Title Anatomical Record-Advances in Integrative Anatomy and Evolutionary Biology. - : Wiley - ISSN 1932-8486
Roč. 295, č. 8 (2012), s. 1364-1372Number of pages 9 s. Language eng - English Country US - United States Keywords aging ; confocal microscopy ; myosin heavy chain ; immunohistochemistry ; muscle fiber types Subject RIV FH - Neurology R&D Projects LC06063 GA MŠMT - Ministry of Education, Youth and Sports (MEYS) MEB090910 GA MŠMT - Ministry of Education, Youth and Sports (MEYS) Institutional support FGU-C - RVO:67985823 CEZ AV0Z50110509 - FGU-C (2005-2011) UT WOS 000306066700013 DOI 10.1002/ar.22512 Annotation In contrast to limb muscles where neonatal myosin (MyHC-neo) is present only shortly after birth, adult masseter muscles contain a substantial portion of MyHC-neo, which is coexpressed with mature MyHC isoforms. We conclude that the diminished expression of MyHC-neo with age could point to a lower regeneration capacity of masseter muscle in the elderly Workplace Institute of Physiology Contact Lucie Trajhanová, lucie.trajhanova@fgu.cas.cz, Tel.: 241 062 400 Year of Publishing 2013
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