The relationship between mtDNA 9205delTA heteroplasmy and structure and function of ATP synthase

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SYSNO ASEP	0320642
Document Type	A - Abstract
R&D Document Type	The record was not marked in the RIV
R&D Document Type	Není vybrán druh dokumentu
Title	The relationship between mtDNA 9205delTA heteroplasmy and structure and function of ATP synthase
Title	Vztah mezi heteroplazmií mutace 9205delTA v mtDNA a strukturou a funkcí ATP synthasy
Author(s)	Hejzlarová, Kateřina (FGU-C) Ješina, Pavel (FGU-C) Kaplanová, Vilma (FGU-C)_{RID, ORCID} Drahota, Zdeněk (FGU-C)_{RID, ORCID} Kalous, Martin (FGU-C) Houštěk, Josef (FGU-C)_{RID, ORCID}
Source Title	Euromit 7. - Stockholm : -, 2008 S. 62-62
Number of pages	1 s.
Action	European Meeting on Mitochondrial Pathology /7./
Event date	11.06.2008-14.06.2008
VEvent location	Stockholm
Country	SE - Sweden
Event type	EUR
Language	eng - English
Country	SE - Sweden
Keywords	spo2 ; mitochondrial DNA ; heteroplasmy ; threshold effect
Subject RIV	CE - Biochemistry
CEZ	AV0Z50110509 - FGU-C (2005-2011)
Annotation	Patients with mtDNA 9205delTA mutation are characterized by different clinical pictures. Using transmitochondrial cybrids, mutation manifestation with respect to the mutation load was analyzed. Our results demonstrate, that functional and structural affection embody threshold effect, probably from the gene-protein level
Workplace	Institute of Physiology
Contact	Lucie Trajhanová, lucie.trajhanova@fgu.cas.cz, Tel.: 241 062 400
Year of Publishing	2009

Number of the records: 1