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"Baseline" Problems in Very Short Echo-time Proton MR Spectroscopy of Low Molecular Weight Metabolites in the Brain
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SYSNO ASEP 0205374 Document Type C - Proceedings Paper (int. conf.) R&D Document Type Conference Paper Title "Baseline" Problems in Very Short Echo-time Proton MR Spectroscopy of Low Molecular Weight Metabolites in the Brain Author(s) Starčuk, Zenon (UPT-D) RID
Starčuk jr., Zenon (UPT-D) RID, ORCID, SAI
Horký, Jaroslav (UPT-D) RIDSource Title Proceedings of the 3nd International Conference on Measurement - Measurement 2001 / Frollo I. ; Plačková A.. - Bratislava : Institute of Measurement Science, Slovak Academy of Sciences, 2001 - ISBN 80-967402-5-3 Pages s. 89-92 Number of pages 4 s. Action Measurement 2001 /3./ Event date 14.05.2001-17.05.2001 VEvent location Smolenice Country SK - Slovakia Event type WRD Language eng - English Country SK - Slovakia Keywords short echo-time proton MR spectra ; metabolite signals Subject RIV JA - Electronics ; Optoelectronics, Electrical Engineering R&D Projects IAA4065901 GA AV ČR - Academy of Sciences of the Czech Republic (AV ČR) CEZ AV0Z2065902 - UPT-D Annotation Accurate and reliable quantification of low molecular weight metabolites in short echo-time proton MR spectra of the brain is usually considerably complicated by an uncharacterized broad baseline extending over the whole frequency range of the metabolite signals of interest. Several sequences providing pure MR spectra of cerebral metabolites were designed, computer analyzed and experimentally tested. In these sequences, precautions have been made to avoid baseline contributions due to experimental imperfections, and signals of low molecular weight metabolites were distinguished from those of macromolecules (lipids), which are substantial contributors to the broad baseline, by utilizing the differences between their T1relaxation times. Workplace Institute of Scientific Instruments Contact Martina Šillerová, sillerova@ISIBrno.Cz, Tel.: 541 514 178 Year of Publishing 2002
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