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A facile synthesis of 9-deaza analogue of olomoucine
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SYSNO ASEP 0194800 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Ostatní články Title A facile synthesis of 9-deaza analogue of olomoucine Author(s) Čapek, Petr (UOCHB-X)
Otmar, Miroslav (UOCHB-X) RID
Masojídková, Milena (UOCHB-X)
Votruba, Ivan (UOCHB-X) RID
Holý, Antonín (UOCHB-X)Source Title Collection of Czechoslovak Chemical Communications. - : Ústav organické chemie a biochemie AV ČR, v. v. i. - ISSN 0010-0765
Roč. 68, č. 4 (2003), s. 779-791Number of pages 13 s. Language eng - English Country CZ - Czech Republic Keywords purines ; antitumor activity ; cytostatics Subject RIV CC - Organic Chemistry R&D Projects OC D13.20 GA MŠMT - Ministry of Education, Youth and Sports (MEYS) CEZ AV0Z4055905 - UOCHB-X Annotation 9-Deaza analogue of cytokinin olomoucine was synthesized without showing any considerable cytostatic activity. Antiproliferative activity on CCRF-CEM cells (IC50=13.3ćM) was found in 6-(benzylamino)-9-deazapurine. Workplace Institute of Organic Chemistry and Biochemistry Contact asep@uochb.cas.cz ; Kateřina Šperková, Tel.: 232 002 584 ; Jana Procházková, Tel.: 220 183 418 Year of Publishing 2004
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