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Administration of liposomal muramyl tripeptide phosphatidylethanolamine (MTP-PE) and diclofenac in the combination attenuates their anti-tumor activities
- 1.0126930 - BFU-R 20033011 RIV SK eng J - Journal Article
Fedoročko, P. - Hoferová, Zuzana - Hofer, Michal - Brezáni, P.
Administration of liposomal muramyl tripeptide phosphatidylethanolamine (MTP-PE) and diclofenac in the combination attenuates their anti-tumor activities.
Neoplasma. Roč. 50, č. 3 (2003), s. 176-184. ISSN 0028-2685. E-ISSN 1338-4317
R&D Projects: GA AV ČR IBS5004009; GA AV ČR KSK5011112
Grant - others:VEGA MŠ SR(SK) 1/9211/02
Institutional research plan: CEZ:AV0Z5004920
Keywords : muramyl tripeptide * diclofenac * NSAIDs
Subject RIV: BO - Biophysics
Impact factor: 0.782, year: 2003
Liposomal muramyl tripeptide phosphatidylethanolamine (MTP-PE), an immunomodulator, and diclofenac, an inhibitor of prostaglandin production, were shown earlier to have anti-tumour effects. In the experiments described in this communication it was shown that combined treatment of mice bearing fibrosarcoma tumours with the above two substances attenuated their anti-tumour activities.
Permanent Link: http://hdl.handle.net/11104/0025157
Number of the records: 1