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Green synthesis of bimetallic ZnO-CuO nanoparticles and their cytotoxicity properties
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SYSNO ASEP 0549736 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve WOS Title Green synthesis of bimetallic ZnO-CuO nanoparticles and their cytotoxicity properties Author(s) Cao, Y. (CN)
Dhahad, H. A. (IQ)
El-Shorbagy, M. A. (SA)
Alijani, H. Q. (IR)
Zakeri, M. (IR)
Heydari, A. (SK)
Bahonar, E. (IR)
Šlouf, Miroslav (UMCH-V) RID, ORCID
Khatami, M. (IR)
Naderifar, M. (IR)
Iravani, S. (IR)
Khatami, S. (IR)
Dehkordi, F. F. (IR)Article number 23479 Source Title Scientific Reports. - : Nature Publishing Group - ISSN 2045-2322
Roč. 11, č. 1 (2021)Number of pages 8 s. Language eng - English Country GB - United Kingdom Keywords green synthesis ; bimetallic nanoparticles ; anticancer activity Subject RIV CD - Macromolecular Chemistry OECD category Polymer science Method of publishing Open access Institutional support UMCH-V - RVO:61389013 UT WOS 000727615800059 EID SCOPUS 85120903594 DOI 10.1038/s41598-021-02937-1 Annotation In this study, a simple and green strategy was reported to prepare bimetallic nanoparticles (NPs) by the combination of zinc oxide (ZnO) and copper oxide (CuO) using Sambucus nigra L. extract. The physicochemical properties of these NPs such as crystal structure, size, and morphology were studied by X-ray diffraction (XRD), field emission gun scanning electron microscopy (FEG-SEM), and transmission electron microscopy (TEM). The results suggested that these NPs contained polygonal ZnO NPs with hexagonal phase and spherical CuO NPs with monoclinic phase. The anticancer activity of the prepared bimetallic NPs was evaluated against lung and human melanoma cell lines based on MTT assay. As a result, the bimetallic ZnO/CuO NPs exhibited high toxicity on melanoma cancer cells while their toxicity on lung cancer cells was low. Workplace Institute of Macromolecular Chemistry Contact Eva Čechová, cechova@imc.cas.cz ; Tel.: 296 809 358 Year of Publishing 2022 Electronic address https://www.nature.com/articles/s41598-021-02937-1
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