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Microscopic study of bovine serum albumin adsorption on zinc oxide (0001) surface
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SYSNO ASEP 0541730 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve WOS Title Microscopic study of bovine serum albumin adsorption on zinc oxide (0001) surface Author(s) Rezek, B. (CZ)
Hematian, H. (CZ)
Jíra, J. (CZ)
Rutherford, D. (CZ)
Kuliček, J. (CZ)
Ukraintsev, Egor (FZU-D) RID, ORCID
Remeš, Zdeněk (FZU-D) RID, ORCIDNumber of authors 7 Article number 2000558 Source Title Physica Status Solidi A : Applications and Materials Science. - : Wiley - ISSN 1862-6300
Roč. 218, č. 6 (2021)Number of pages 6 s. Language eng - English Country DE - Germany Keywords adhesions ; albumin ; atomic force microscopy ; force fields ; zinc oxide Subject RIV BM - Solid Matter Physics ; Magnetism OECD category Nano-materials (production and properties) R&D Projects GC19-02858J GA ČR - Czech Science Foundation (CSF) LM2018110 GA MŠMT - Ministry of Education, Youth and Sports (MEYS) Method of publishing Limited access Institutional support FZU-D - RVO:68378271 UT WOS 000611659700001 EID SCOPUS 85099978293 DOI 10.1002/pssa.202000558 Annotation Properties and functions of various ZnO materials are intensively investigated in biological systems for diagnostics, therapy, health risks assessment as well as bactericidal and decontamination purposes. Herein, the interface between ZnO and biological environment is studied by characterizing adsorption of bovine serum albumin (BSA) and fetal bovine serum (FBS) using atomic force microscopy with CF4-treated tips. Similar molecular morphologies (thickness around 2 nm) yet different binding forces to ZnO (10-25 nN) are observed. These observations are corroborated by atomic scale simulations of BSA on (0001) ZnO surface using force-field method and showing rearrangements of Zn surface atoms. Such binding may have an impact also on other properties of ZnO-BSA complex. Workplace Institute of Physics Contact Kristina Potocká, potocka@fzu.cz, Tel.: 220 318 579 Year of Publishing 2022 Electronic address https://doi.org/10.1002/pssa.202000558
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