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Xanthones Content in Swertia multicaulis D. Don from Nepal
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SYSNO ASEP 0494635 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve WOS Title Xanthones Content in Swertia multicaulis D. Don from Nepal Author(s) Timsina, B. (CZ)
Kindlmann, P. (CZ)
Rokaya, Maan Bahadur (BU-J) RID, ORCID
Vrchotová, N. (CZ)
Tříska, J. (CZ)
Horník, Š. (CZ)
Sýkora, J. (CZ)Article number 1067 Source Title Molecules. - : MDPI
Roč. 23, č. 5 (2018), s. 1-8Number of pages 8 s. Language eng - English Country CH - Switzerland Keywords secondary metabolites ; phytochemistry ; Swertia, Gentianaceae Subject RIV EF - Botanics OECD category Plant sciences, botany Institutional support BU-J - RVO:67985939 UT WOS 000435204000082 EID SCOPUS 85046635552 DOI 10.3390/molecules23051067 Annotation The medicinal plant Swertia multicaulis D. Don was collected in Rasuwa District (Nepal) and the xanthone content of its ethyl acetate extracts was studied. The total amount of xanthones in S. multicaulis determined by HPLC reaches almost 13 g of xanthones per 1 kg of dry matter. The identification of xanthones in S. multicaulis was achieved by a combination of HPLC, LC–MS and LC–NMR. The final assignment of the individual chemical structures was provided by NMR, supported by preparative HPLC. In eight chromatographic peaks, four major xanthones were identified—1,3-dihydroxy-5,8-dimethoxyxanthone, 1-hydroxy-3,5,8-trimethoxyxanthone, bellidifolin (1,5,8-tri-hydroxy-3-methoxyxanthone), and decussatin (1-hydroxy-3,7,8-trimethoxyxanthone). Workplace Institute of Botany Contact Martina Bartošová, martina.bartosova@ibot.cas.cz, ibot@ibot.cas.cz, Tel.: 271 015 242 ; Marie Jakšová, marie.jaksova@ibot.cas.cz, Tel.: 384 721 156-8 Year of Publishing 2019
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