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Are Subthalamicus Nucleus, Internal, Globus Pallidus and Thalamus Involved in Thinking?
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SYSNO ASEP 0455912 Document Type A - Abstract R&D Document Type The record was not marked in the RIV R&D Document Type Není vybrán druh dokumentu Title Are Subthalamicus Nucleus, Internal, Globus Pallidus and Thalamus Involved in Thinking? Author(s) Minks, E. (CZ)
Jurák, Pavel (UPT-D) RID, ORCID, SAI
Chládek, Jan (UPT-D) RID, ORCID, SAI
Hummelová, Z. (CZ)Number of authors 4 Source Title Journal of Neurology Neurosurgery and Psychiatry - ISSN 0022-3050
Roč. 86, e4 (2015), s. 46Number of pages 1 s. Publication form Print - P Action Annual Meeting of the Association-of-British-Neurologists (ABN) Event date 10.09.2015 VEvent location London Country GB - United Kingdom Event type WRD Language eng - English Country GB - United Kingdom Keywords Subthalamicus Nucleus ; Globus Pallidus ; Involving Thinking Subject RIV BH - Optics, Masers, Lasers Institutional support UPT-D - RVO:68081731 Annotation The aim was to compare evoked potentials (EP) from the P300 paradigm against mismatch negativity (MMN) paradigm, both recorded in the subthalamic nucleus (STN), internal globus pallidus (GPi) and thalamus (Th) and thus electrophysiologically isolate conscious cognition component in these structures. We included 8 patients in Deep brain stimulation program and recorded EP (patients with Parkinson's disease, Generalized dystonia, Essential tremor, Epilepsy). The two four-contacts intracerebral electrodes were implanted into the left and right STN, GPi or Th bilaterally. We computed local potentials on the left and right electrode and we studied the latency of cognitive response (from 200 to 400 ms). In the comparison of infrequent stimuli related P300 and MMN a significant difference was found in 14 from 16 electrodes. Comparing frequent answers we found significant difference in 13 from 16 electrodes. The difference between evoked potentials of MMN and P300 protocols in 200–400 ms latency suggests that STN, GPi and Th are involved in conscious cognitive processes at the time of stimuli application. Workplace Institute of Scientific Instruments Contact Martina Šillerová, sillerova@ISIBrno.Cz, Tel.: 541 514 178 Year of Publishing 2016
Number of the records: 1