Number of the records: 1  

Are Subthalamicus Nucleus, Internal, Globus Pallidus and Thalamus Involved in Thinking?

  1. 1.
    SYSNO ASEP0455912
    Document TypeA - Abstract
    R&D Document TypeThe record was not marked in the RIV
    R&D Document TypeNení vybrán druh dokumentu
    TitleAre Subthalamicus Nucleus, Internal, Globus Pallidus and Thalamus Involved in Thinking?
    Author(s) Minks, E. (CZ)
    Jurák, Pavel (UPT-D) RID, ORCID, SAI
    Chládek, Jan (UPT-D) RID, ORCID, SAI
    Hummelová, Z. (CZ)
    Number of authors4
    Source TitleJournal of Neurology Neurosurgery and Psychiatry - ISSN 0022-3050
    Roč. 86, e4 (2015), s. 46
    Number of pages1 s.
    Publication formPrint - P
    ActionAnnual Meeting of the Association-of-British-Neurologists (ABN)
    Event date10.09.2015
    VEvent locationLondon
    CountryGB - United Kingdom
    Event typeWRD
    Languageeng - English
    CountryGB - United Kingdom
    KeywordsSubthalamicus Nucleus ; Globus Pallidus ; Involving Thinking
    Subject RIVBH - Optics, Masers, Lasers
    Institutional supportUPT-D - RVO:68081731
    AnnotationThe aim was to compare evoked potentials (EP) from the P300 paradigm against mismatch negativity (MMN) paradigm, both recorded in the subthalamic nucleus (STN), internal globus pallidus (GPi) and thalamus (Th) and thus electrophysiologically isolate conscious cognition component in these structures. We included 8 patients in Deep brain stimulation program and recorded EP (patients with Parkinson's disease, Generalized dystonia, Essential tremor, Epilepsy). The two four-contacts intracerebral electrodes were implanted into the left and right STN, GPi or Th bilaterally. We computed local potentials on the left and right electrode and we studied the latency of cognitive response (from 200 to 400 ms). In the comparison of infrequent stimuli related P300 and MMN a significant difference was found in 14 from 16 electrodes. Comparing frequent answers we found significant difference in 13 from 16 electrodes. The difference between evoked potentials of MMN and P300 protocols in 200–400 ms latency suggests that STN, GPi and Th are involved in conscious cognitive processes at the time of stimuli application.
    WorkplaceInstitute of Scientific Instruments
    ContactMartina Šillerová, sillerova@ISIBrno.Cz, Tel.: 541 514 178
    Year of Publishing2016
Number of the records: 1  

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