Diverse development and higher sensitivity of the circadian clocks to changes in maternal-feeding regime in a rat model of cardio-metabolic disease

Number of the records: 1

1.

SYSNO ASEP	0446426
Document Type	J - Journal Article
R&D Document Type	Journal Article
Subsidiary J	Článek ve WOS
Title	Diverse development and higher sensitivity of the circadian clocks to changes in maternal-feeding regime in a rat model of cardio-metabolic disease
Author(s)	Olejníková, Lucie (FGU-C) Polidarová, Lenka (FGU-C)_{RID, ORCID} Paušlyová, Lucia (FGU-C) Sládek, Martin (FGU-C)_{RID, ORCID, SAI} Sumová, Alena (FGU-C)_{RID, ORCID}
Source Title	Chronobiology International - ISSN 0742-0528 Roč. 32, č. 4 (2015), s. 531-547
Number of pages	17 s.
Language	eng - English
Country	GB - United Kingdom
Keywords	circadian clock ; clock gene ; colon ; liver ; SHR ; supraciasmatic nucleus
Subject RIV	ED - Physiology
R&D Projects	GAP303/12/1108 GA ČR - Czech Science Foundation (CSF)
Institutional support	FGU-C - RVO:67985823
UT WOS	000353925700009
EID SCOPUS	84928897656
DOI	10.3109/07420528.2015.1014095
Annotation	This study was aimed to elucidate how the SHR circadian system develops during ontogenesis. Our findings revealed diverse development and higher sensitivity of the developing circadian clocks of SHR to maternal cues. They suggested that these aberrancies might contribute to the metabolic disease, which SHR spontaneously develop in adulthood
Workplace	Institute of Physiology
Contact	Lucie Trajhanová, lucie.trajhanova@fgu.cas.cz, Tel.: 241 062 400
Year of Publishing	2016

Number of the records: 1