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Diverse development and higher sensitivity of the circadian clocks to changes in maternal-feeding regime in a rat model of cardio-metabolic disease
- 1.0446426 - FGÚ 2016 RIV GB eng J - Journal Article
Olejníková, Lucie - Polidarová, Lenka - Paušlyová, Lucia - Sládek, Martin - Sumová, Alena
Diverse development and higher sensitivity of the circadian clocks to changes in maternal-feeding regime in a rat model of cardio-metabolic disease.
Chronobiology International. Roč. 32, č. 4 (2015), s. 531-547. ISSN 0742-0528. E-ISSN 1525-6073
R&D Projects: GA ČR(CZ) GAP303/12/1108
Grant - others:Program interní podpory projektů mezinárodní spolupráce AV ČR(CZ) M200111202
Institutional support: RVO:67985823
Keywords : circadian clock * clock gene * colon * liver * SHR * supraciasmatic nucleus
Subject RIV: ED - Physiology
Impact factor: 3.540, year: 2015
This study was aimed to elucidate how the SHR circadian system develops during ontogenesis. Our findings revealed diverse development and higher sensitivity of the developing circadian clocks of SHR to maternal cues. They suggested that these aberrancies might contribute to the metabolic disease, which SHR spontaneously develop in adulthood
Permanent Link: http://hdl.handle.net/11104/0248424
Number of the records: 1