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Interaction of antidepressant drug fluoxetine with the metabolism of triiodothyronine
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SYSNO ASEP 0432122 Document Type C - Proceedings Paper (int. conf.) R&D Document Type The record was not marked in the RIV Title Interaction of antidepressant drug fluoxetine with the metabolism of triiodothyronine Author(s) Pavelka, Stanislav (FGU-C) RID Source Title Proceedings of the 7th International Symposium on Trace Elements in Human: New Perspectives. - Athens : University of Athens, 2009 Pages s. 178-184 Action International Symposium on Trace Elements in Human : New Perspectives /7./ Event date 13.10.2009-15.10.2009 VEvent location Athens Country GR - Greece Event type EUR Language eng - English Country GR - Greece Keywords antidepressant drug ; metabolism ; thyroid hormone Subject RIV ED - Physiology R&D Projects GA304/08/0256 GA ČR - Czech Science Foundation (CSF) CEZ AV0Z50110509 - FGU-C (2005-2011) Annotation In the present study, we followed the effects of subchronic administration (for 25 days) of antidepressant drug fluoxetine, alone or in combination with 3,5,3’-triiodothyronine (T3), on the metabolism of thyroid hormones in the rat. For this reason, we used radiometric enzyme assays for iodothyronine sulfotransferases (ST) and UDP-glucuronyltransferase (GT), as well as our newly developed radiometric assays for iodothyronine deiodinases of types 1, 2 and 3 (D1, D2 and D3). Workplace Institute of Physiology Contact Lucie Trajhanová, lucie.trajhanova@fgu.cas.cz, Tel.: 241 062 400 Year of Publishing 2015
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