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Sequential Shh expression in the development of the mouse upper functional incisor
- 1.0397915 - ÚEM 2014 RIV US eng J - Journal Article
Hovořáková, Mária - Smrčková, Lucie - Lesot, H. - Lochovská, Kateřina - Peterka, Miroslav - Peterková, Renata
Sequential Shh expression in the development of the mouse upper functional incisor.
Journal of Experimental Zoology Part B: Molecular and Developmental Evolution Additional Title Information. Roč. 320, č. 7 (2013), s. 455-464. ISSN 1552-5007. E-ISSN 1552-5015
R&D Projects: GA ČR GA304/09/1579; GA ČR(CZ) GAP305/12/1766
Institutional support: RVO:68378041
Keywords : mouse * craniofacial * ED13.5
Subject RIV: EB - Genetics ; Molecular Biology
Impact factor: 1.876, year: 2013
This study brings new insights into the early development of the upper incisor in mice and completes the data on normal mouse incisor development. The temporal-spatial pattern of Shh expression reflects the development of two tooth generations, being detectable in two successive, antero-posteriorly located areas in the prospective incisor region in the upper jaw. The first, anterior and superficial Shh expression domain reflects the rudimentary tooth development suppressed during evolution. Only the subsequent, posterior and deeper Shh expression region, appearing at ED13.5, correlates with the prospective upper functional incisor in wild-type mice.
Permanent Link: http://hdl.handle.net/11104/0225536
Number of the records: 1