Effect of tetraalkylammonium cations on amperometric detection of heparin at a polarized water/ionic liquid membrane interface

0392976 - ÚFCH JH 2014 RIV CZ eng C - Conference Paper (international conference)
Samec, Zdeněk - Langmaier, Jan - Samcová, E. - Tůma, P.
Effect of tetraalkylammonium cations on amperometric detection of heparin at a polarized water/ionic liquid membrane interface.
XXXIII. Moderní elektrochemické metody. Sborník přednášek. Ústí nad Labem: Best servis, 2013 - (Navrátil, T.; Fojta, M.; Pecková, K.), s. 167-171. ISBN 978-80-905221-1-4.
[Moderní elektrochemické metody /33./. Jetřichovice (CZ), 20.05.2013-24.05.2013]
R&D Projects: GA ČR GAP206/11/0707
Institutional support: RVO:61388955
Keywords : Heparin * Ionic liquid membrane * Amperometric detection
Subject RIV: CG - Electrochemistry

Amperometric detection of heparin, which combines the spontaneous extraction of heparin into the ionic liquid (IL) membrane with its potential-driven stripping, is studied using IL composed of the tetradodecylammonium (TDDA+) cation and tetrakis[3,5-bis(trifluoro-methyl)phenyl]borate (TFPB-). In contrast to the IL membrane composed of tridodecylmethylammonium cation (TDMA+) and TFPB-, no promotion effect of the tetrapentylammonium cation (TPeA+) is observed. The absence of the effect is ascribed to a much weaker ion association between heparin and TDDA+, which does not support the accumulation of heparin into the IL phase.
Permanent Link: http://hdl.handle.net/11104/0221737