Measures of linkage disequilibrium among neighboring snps indicate asymmetries across the house mouse hybrid zone

0374427 - ÚBO 2012 FR eng A - Abstract
Wang, L. - Luzynski, K. - Pool, J. E. - Janoušek, V. - Dufková, Petra - Mrkvicová Vyskočilová, Martina - Teeter, K. C. - Nachman, M. W. - Munclinger, P. - Macholán, Miloš - Piálek, Jaroslav - Tucker, P. K.
Measures of linkage disequilibrium among neighboring snps indicate asymmetries across the house mouse hybrid zone.
ECM 2011. VIth EuropeanCongress of Mammalogy. Paris: Université P. et M. Curie, 2011 - (Denys, C.). s. 44
[European Congress of Mammalogy /7./. 19.07.2011-23.07.2011, Paris]
Institutional research plan: CEZ:AV0Z60930519; CEZ:AV0Z50450515
Keywords : house mouse * hybrid zone
Subject RIV: EG - Zoology
http://www.alphavisa.com/ecm2011/pdf/ECM2011-Abstract_Book.pdf

Theory predicts that naturally occurring hybrid zones between genetically distinct taxa can move over space and time as a result of selection and/or demographic processes, with certain types of hybrid zones being more or less likely to move. Determining whether a hybrid zone is stationary or moving has important implications for understanding evolutionary processes affecting interactions in hybrid populations. However, direct observations of hybrid zone movement are difficult to make unless the zone is moving rapidly. Here evidence for movement in the house mouse Mus musculus domesticus Mus musculus musculus hybrid zone is provided using measures of LD and haplotype structure among neighboring SNP markers from across the genome. Local populations of mice across two transects in Germany and the Czech Republic were sampled and a total of 1301 mice were genotyped at 1401 markers from the nuclear genome. Empirical measures of LD provide evidence for extinction and (re)colonization in single populations and together with simulations suggest hybrid zone movement due to either geographydependent asymmetrical dispersal or selection favoring one subspecies over the other.
Permanent Link: http://hdl.handle.net/11104/0207351