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Developmentally regulated expression of the transmembrane adaptor protein TRIM in fetal and adult T cells
- 1.0191344 - UMG-J 20010414 RIV GB eng J - Journal Article
Huynh, T. - Wurch, A. - Bruyns, E. - Kořínek, Vladimír - Schraven, B. - Eichmann, K.
Developmentally regulated expression of the transmembrane adaptor protein TRIM in fetal and adult T cells.
Scandinavian Journal of Immunology. Roč. 54, 1-2 (2001), s. 146-154. ISSN 0300-9475. E-ISSN 1365-3083
Institutional research plan: CEZ:AV0Z5052915
Keywords : TCR * TRIM * thymocytes
Subject RIV: EB - Genetics ; Molecular Biology
Impact factor: 1.739, year: 2001
Expression of mRNA of the adaptor protein TRIM associated with TCR was detected in all mainstream thymocyte subsets in adult mice. TRIM protein appears in the CD44+ CD25+ subset of adult double negative cells thymocytes. In fetal and adult thymocytes, TRIM protein expression was highest in DN2, DN3 (CD44-25+) and in DP cells, compatibel with a functional role at thymic selection.
Permanent Link: http://hdl.handle.net/11104/0087097
Number of the records: 1