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Effect of ionising radiation on the labelling of closo-dodecaborate(2-)anion with .SUP.125 I
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SYSNO ASEP 0185192 Document Type C - Proceedings Paper (int. conf.) R&D Document Type Conference Paper Title Effect of ionising radiation on the labelling of closo-dodecaborate(2-)anion with .SUP.125 I Author(s) Lebeda, Ondřej (UJF-V) RID, ORCID, SAI
Tolmachev, V. (SE)
Orlova, A. (SE)
Lundquist, H. (SE)
Carlsson, J. (SE)
Sjöberg, S. (SE)Source Title Proceedings of the Conference "Contemporary Boron Chemistry" / Davidson M. ; Hughes A. K. ; Marder T. B. ; Wade K.. - Cambridge : The Royal Society of Chemistry, 2000 Pages s. 148-151 Number of pages 4 s. Action Conference "Contemporary Boron Chemistry" Event date 11.07.1999-15.07.1999 VEvent location Durham Country GB - United Kingdom Language eng - English Country GB - United Kingdom Subject RIV BG - Nuclear, Atomic and Molecular Physics, Colliders CEZ AV0Z1048901 - UJF-V Annotation The organic derivatives of dodecahydro-closo-dodecaborate (2-)anion have been suggested as prosthetic groups for attachment of radiohalogens to proteins. Since spontaneous labelling of closo-dodecaborate anion does not practically occur, the Chloramine-T or other oxidants are used. However, the astatination of boron cages with .sub.211 At makes an exception. The cause of this phenomenon could be intensive alpha radiation of .sub.211 At, subsequent radiolysis ofsolvent and oxidation agents production. The aim of this study was, therefore, to investigate the impact of ionising radiation on the closo-dodecaborate (2-) anion labelling with.sub.125 I. Workplace Nuclear Physics Institute Contact Markéta Sommerová, sommerova@ujf.cas.cz, Tel.: 266 173 228 Year of Publishing 2001
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