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Signal transduction and cardiac hypertrophy
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SYSNO ASEP 0142414 Document Type M - Monograph Chapter R&D Document Type Monograph Chapter Title Role of mitochondrial K(ATP) channels in improved ischemic tolerance of chronically hypoxic adult and immature hearts Author(s) Kolář, František (FGU-C) RID, ORCID, SAI
Ošťádalová, Ivana (FGU-C) RID
Ošťádal, Bohuslav (FGU-C) RID, ORCID
Neckář, Jan (FGU-C) RID, ORCID
Szárszoi, Ondrej (FGU-C)ISBN 1-4020-7218-X Source Title Signal transduction and cardiac hypertrophy. - Boston : Kluwer Academic Publishers, 2003 / Dhalla N.S. ; Hryshko L.V. ; Kardami E. ; Singal P.K. Pages s. 69-83 Number of pages 15 s. Action World Heart Congress /17./ Event date 06.07.2001-11.07.2001 VEvent location Winnipeg Country CA - Canada Event type WRD Language eng - English Country US - United States Keywords chronic hypoxia ; myocardial ischemia ; protection Subject RIV ED - Physiology R&D Projects GA305/01/0279 GA ČR - Czech Science Foundation (CSF) GA305/00/1659 GA ČR - Czech Science Foundation (CSF) LN00A069 GA MŠMT - Ministry of Education, Youth and Sports (MEYS) CEZ AV0Z5011922 - FGU-C Annotation Chronic hypoxia and preconditioning increase cardiac tolerance to ischemic injury but the two phenomena are not additive. Newborn hearts are more resistant than adults and cannot be preconditioned. Mechanism of protection by chronic hypoxia involves mitochondrial K(ATP) channels. Workplace Institute of Physiology Contact Lucie Trajhanová, lucie.trajhanova@fgu.cas.cz, Tel.: 241 062 400 Year of Publishing 2004
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