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Spatial arrangement of genes, centromeres and chromosomes in human blood cell nuclei and its changes during the cell cycle, differntiation and after irradiation

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    0126439 - BFU-R 20010259 RIV NL eng J - Journal Article
    Skalníková, M. - Kozubek, Stanislav - Lukášová, Emilie - Bártová, Eva - Jirsová, Pavla - Cafourková, Alena - Koutná, I. - Kozubek, Michal
    Spatial arrangement of genes, centromeres and chromosomes in human blood cell nuclei and its changes during the cell cycle, differntiation and after irradiation.
    Chromosome Research. Roč. 8, - (2000), s. 487-499. ISSN 0967-3849. E-ISSN 1573-6849
    R&D Projects: GA MŠMT VS97031; GA MZd NM15; GA AV ČR IBS5004010
    Institutional research plan: CEZ:AV0Z5004920
    Subject RIV: BO - Biophysics
    Impact factor: 1.725, year: 2000

    The results show that different genetic loci (genes and centromeres) are located in specific subregions of cell nuclei which form distinct layers at defined centre-of-nucleus to locus distance. Some chromosomes are polarized with genes located in the inner parts of the nucleus and centromere on the nuclear periphery.
    Permanent Link: http://hdl.handle.net/11104/0024669

     
     

Number of the records: 1  

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