Number of the records: 1

DeutEx

SYSNO ASEP	0550855
Document Type	L4 - Software
R&D Document Type	Software
Title	DeutEx
Author(s)	Kavan, Daniel (MBU-M)_{RID, ORCID} Kádek, Alan (MBU-M)_{RID, ORCID} Kruppa, G. H. (US) Man, Petr (MBU-M)_{RID, ORCID}
Year of issue	2021
Int.Code	DeutEx
Technical parameters	Samostatný program sestavený v jazyce java fungující na běžných výpočetních strojích pod systémy Unix/Linux, Windows a MAC OC
Economic parameters	Zvýšení prostupnosti analýz a snazší interpretace dat v HDX-MS analýzách.
Owner Name	Mikrobiologický ústav AV ČR, v. v. i.
Registration Number of the result owner	61388971
License fee fee	A - Poskytovatel licence požaduje licenční poplatek
Language	eng - English
Country	CZ - Czech Republic
Keywords	Java application ; mass spectrometric data ; hydrogen/deuterium exchange
Subject RIV	CE - Biochemistry
OECD category	Biochemical research methods
R&D Projects	GA19-16084S GA ČR - Czech Science Foundation (CSF)
	GA16-24309S GA ČR - Czech Science Foundation (CSF)
	GA16-20860S GA ČR - Czech Science Foundation (CSF)
	GF16-34818L GA ČR - Czech Science Foundation (CSF)
	GAP206/12/0503 GA ČR - Czech Science Foundation (CSF)
	LD15089 GA MŠMT - Ministry of Education, Youth and Sports (MEYS)
Institutional support	MBU-M - RVO:61388971
Annotation	Anotace v jazyce práceDeutEx is a Java-based standalone application enabling fully automated processing of mass spectrometric data from hydrogen/deuterium exchange experiments. It has three main interfaces where user can perform 1) peptide mapping – assembly of the main input file for subsequent calculations, 2) manage the data and organize them according to experimental conditions, 3) run the calculation, fully review and export the resulting data. The program needs LCMS data exported in text files and can be thus compatible with a majority of MS instrumentation. The output is either graphical (uptake plots) or simple text files organized according to the community guidelines or compatible with a web-based application MSTools. The program calculates percentage of deuteration, number of exchanged deuterons, signal intensity and peak-width. It can manage numerous experimental conditions, replicates and different protein sequences. It can handle any protein modification and mutations.
Workplace	Institute of Microbiology
Contact	Eliška Spurná, eliska.spurna@biomed.cas.cz, Tel.: 241 062 231
Year of Publishing	2022
Electronic address	www.deutex.org

Number of the records: 1