Study of gamma-ray emission by proton beam interaction with injected Boron atoms for future medical imaging applications

0483609 - FZÚ 2018 RIV GB eng J - Journal Article
Petringa, G. - Cirrone, G. A. P. - Caliri, C. - Cuttone, G. - Giuffrida, Lorenzo - Larosa, G. - Manna, R. - Manti, L. - Marchese, V. - Marchetta, C. - Margarone, Daniele - Milluzzo, G. - Picciotto, A. - Romano, F. - Romano, F.P. - Russo, A.D. - Russo, G. - Santonocito, D. - Scuderi, Valentina
Study of gamma-ray emission by proton beam interaction with injected Boron atoms for future medical imaging applications.
Journal of Instrumentation. Roč. 12, Mar (2017), s. 1-10, č. článku C03049. ISSN 1748-0221. E-ISSN 1748-0221
R&D Projects: GA MŠMT EF15_008/0000162; GA MŠMT LQ1606
Grant - others:ELI Beamlines(XE) CZ.02.1.01/0.0/0.0/15_008/0000162
Institutional support: RVO:68378271
Keywords : Instrumentation for particle-beam therapy * spallation source targets * radioisotope production * neutrino and muon sources
OECD category: Fluids and plasma physics (including surface physics)
Impact factor: 1.258, year: 2017

In this work an experimental and theoretical study of gamma-prompt emission has been carried out with the main aim being to understand to what extent this approach can be used during a treatment based on proton-boron fusion therapy. An experimental campaign, carried out with a high purity Germanium detector, has been performed to evaluate the gamma emission from two pure B-11 and B-10 targets. Furthermore, a set of analytical simulations, using the Talys nuclear reaction code has been performed and the calculated spectra compared with the experimental results. These comparisons allowed us to successfully validate Talys which was then used to estimate the gamma emission when a realistic Boron concentration was considered.
Permanent Link: http://hdl.handle.net/11104/0278842