Metabolism in time and space – exploring the frontier of developmental biology

0480863 - BC 2018 RIV GB eng J - Journal Article
Krejčí, Alena - Tennessen, J. M.
Metabolism in time and space – exploring the frontier of developmental biology.
Development. Roč. 144, č. 18 (2017), s. 3193-3198. ISSN 0950-1991. E-ISSN 1477-9129
Institutional support: RVO:60077344
Keywords : metabolism * mitochondria * aerobic glycolysis
OECD category: Genetics and heredity (medical genetics to be 3)
Impact factor: 5.413, year: 2017
Method of publishing: Open access
https://cob.silverchair-cdn.com/cob/content_public/journal/dev/144/18/10.1242_dev.150573/10/dev150573.pdf?Expires=1638341167&Signature=G-xR563hlP6QEJTpAmTZlWWtjtK3NlAnN9nY0~S5AuOLv1af-LJQuFpsGWZZqgw88B-c7Q1c12F5WTDqwfZAl7FJKn6BSDkJKiud7zWFcxiU-Dfi-idHbK9I6x-5NBuR692vHKTqbnczkmNDcSGYi9dgCB~3b5mBJ72Qn4ybsooGe1EeKZWdsUWz2L-lvVFjWoNOFrzaSBV42Dmvvk0jWReOyrGVWHI48sjRLpfpknp2E2B4zB6pKsGeLKs-DouDCEyEouD1bReMGR-c6BXOc8dFCDl~EDVe5Hh6fryKX0AK~gi4tlCcDc7n2IsZmM5ZRIelzmePxudeYqJncgKSTA__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA

Despite the fact that metabolic studies played a prominent role in the early history of developmental biology research, the field of developmental metabolism was largely ignored following the advent of modern molecular biology. Metabolism, however, has recently re-emerged as a focal point of biomedical studies and, as a result, developmental biologists are once again exploring the chemical and energetic forces that shape growth, development and maturation. In May 2017, a diverse group of scientists assembled at the EMBO/EMBL Symposium ‘Metabolism in Time and Space’ to discuss how metabolism influences cellular and developmental processes. The speakers not only described how metabolic flux adapts to the energetic needs of a developing organism, but also emphasized that metabolism can directly regulate developmental progression. Overall, and as we review here, this interdisciplinary meeting provided a valuable forum to explore the interface between developmental biology and metabolism.
Permanent Link: http://hdl.handle.net/11104/0276866