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Chitosan hydrogels enriched with polyphenols: Antibacterial activity, cell adhesion and growth and mineralization
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SYSNO ASEP 0444733 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve WOS Title Chitosan hydrogels enriched with polyphenols: Antibacterial activity, cell adhesion and growth and mineralization Author(s) Lišková, Jana (FGU-C) RID, ORCID
Douglas, T.E.L. (BE)
Beranová, J. (CZ)
Skwarczyńska, A. (PL)
Božič, M. (SI)
Samal, S. K. (BE)
Modrzejewska, Z. (PL)
Gorgieva, S. (SI)
Kokol, V. (SI)
Bačáková, Lucie (FGU-C) RID, ORCIDSource Title Carbohydrate Polymers. - : Elsevier - ISSN 0144-8617
Roč. 129, Sep 20 (2015), s. 135-142Number of pages 8 s. Language eng - English Country GB - United Kingdom Keywords hydrogel ; polyphenol ; cytocompatibility Subject RIV EI - Biotechnology ; Bionics R&D Projects ED1.1.00/02.0109 GA MŠMT - Ministry of Education, Youth and Sports (MEYS) EE2.3.30.0025 GA MŠMT - Ministry of Education, Youth and Sports (MEYS) Institutional support FGU-C - RVO:67985823 UT WOS 000356746000018 EID SCOPUS 84929335296 DOI 10.1016/j.carbpol.2015.04.043 Annotation Enrichment of ALP-loaded chitosan hydrogels with PG and GA has no appreciable negative effect on hydrogel gelation kinetics, minneralizability and ability to reduce the colony forming ability of E. coli as well as bacterial growth in liquid medium. Antioxidant activity was quicker and higher in hydrogels containing PG and GA before mineralization. Antioxidant activity of hydrogels containing GA was reduced as a result of mineralization. Addition of GA to hydrogels substantially enhanced the antibacterial activity. PG had no negative effect on MG63 cell adhesion and growth, while GA caused cytotoxicity and diminished cell growth Workplace Institute of Physiology Contact Lucie Trajhanová, lucie.trajhanova@fgu.cas.cz, Tel.: 241 062 400 Year of Publishing 2016
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