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Virucidal Nanofiber Textiles Based on Photosensitized Production of Singlet Oxygen
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SYSNO ASEP 0384371 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve WOS Title Virucidal Nanofiber Textiles Based on Photosensitized Production of Singlet Oxygen Author(s) Lhotáková, Y. (CZ)
Plištil, L. (CZ)
Morávková, A. (CZ)
Kubát, Pavel (UFCH-W) RID, ORCID, SAI
Lang, Kamil (UACH-T) SAI, RID, ORCID
Forstová, J. (CZ)
Mosinger, J. (CZ)Source Title PLoS ONE. - : Public Library of Science - ISSN 1932-6203
Roč. 7, č. 11 (2012), e49226Number of pages 9 s. Language eng - English Country US - United States Keywords photosynthesis ; biomaterials ; nanofiber textiles Subject RIV CF - Physical ; Theoretical Chemistry R&D Projects GAP208/10/1678 GA ČR - Czech Science Foundation (CSF) Institutional support UFCH-W - RVO:61388955 ; UACH-T - RVO:61388980 UT WOS 000311315300072 DOI 10.1371/journal.pone.0049226 Annotation Novel biomaterials based on hydrophilic polycaprolactone and polyurethane (Tecophilic®) nanofibers with an encapsulated 5,10,5,20-tetraphenylporphyrin photosensitizer were prepared by electrospinning. The doped nanofiber textiles efficiently photo-generate O2(1Δg), which oxidize external chemical and biological substrates/targets. Strong photo-virucidal effects toward non-enveloped polyomaviruses and enveloped baculoviruses were observed on the surface of these textiles. The photo-virucidal effect was confirmed by a decrease in virus infectivity. In contrast, no virucidal effect was detected in the absence of light and/or the encapsulated photosensitizer. Workplace J. Heyrovsky Institute of Physical Chemistry Contact Michaela Knapová, michaela.knapova@jh-inst.cas.cz, Tel.: 266 053 196 Year of Publishing 2013
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