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An antagonist of GABA-B receptors potentiates activity of cortical epileptic foci
- 1.0380773 - FGÚ 2013 RIV CZ eng J - Journal Article
Mareš, Pavel - Bernášková, Klára - Kubová, Hana
An antagonist of GABA-B receptors potentiates activity of cortical epileptic foci.
Physiological Research. Roč. 61, č. 3 (2012), s. 325-329. ISSN 0862-8408. E-ISSN 1802-9973
R&D Projects: GA MŠMT(CZ) LC554; GA ČR(CZ) GAP304/10/1274
Institutional research plan: CEZ:AV0Z50110509
Keywords : epileptic focus * GABA-B receptor * cerebral cortex * rat
Subject RIV: FH - Neurology
Impact factor: 1.531, year: 2012
Interictal activity of epileptic foci elicited by bicuculline methiodide was not affected by GABA-B receptor antagonist CGP35348. Ion contrast, ictal episodes appearing spontaneously were significantly potentiated by the antagonist. Results speak in favor of participation of GABA-B receptors in epileptic phenomena generated by cortical-subcortical interaction
Permanent Link: http://hdl.handle.net/11104/0211397
Number of the records: 1