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Toxicity study of antimicrobial peptides from wild bee venom and their analogs toward mammalian normal and cancer cells
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SYSNO ASEP 0379323 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve WOS Title Toxicity study of antimicrobial peptides from wild bee venom and their analogs toward mammalian normal and cancer cells Author(s) Slaninová, Jiřina (UOCHB-X)
Mlsová, V. (CZ)
Kroupová, H. (CZ)
Alán, Lukáš (FGU-C) RID, ORCID
Tůmová, Tereza (UOCHB-X) RID
Monincová, Lenka (UOCHB-X)
Borovičková, Lenka (UOCHB-X)
Fučík, Vladimír (UOCHB-X) RID
Čeřovský, Václav (UOCHB-X) RID, ORCIDNumber of authors 9 Source Title Peptides. - : Elsevier - ISSN 0196-9781
Roč. 33, č. 1 (2012), s. 18-26Number of pages 9 s. Language eng - English Country US - United States Keywords antimicrobial peptides ; venom ; hymenoptera ; cancer cells ; toxicity ; confocal microscopy Subject RIV CE - Biochemistry R&D Projects GA203/08/0536 GA ČR - Czech Science Foundation (CSF) CEZ AV0Z40550506 - UOCHB-X (2005-2011) AV0Z50110509 - FGU-C (2005-2011) UT WOS 000300073100003 DOI 10.1016/j.peptides.2011.11.002 Annotation Cytotoxicity of AMPs from wild bees and some of their analogs was tested toward two normal cell lines and three cancer cell lines. The cancer cells HeLa S3 and CEM were very sensitives to the peptides, for the other cell lines to be killed, the concentrations had to be four to twenty times higher. Workplace Institute of Organic Chemistry and Biochemistry Contact asep@uochb.cas.cz ; Kateřina Šperková, Tel.: 232 002 584 ; Jana Procházková, Tel.: 220 183 418 Year of Publishing 2013
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