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Metalation of 6-halo-2,4-dimethoxypyrimidines as the key step for the synthesis of biologicaly active compounds
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SYSNO ASEP 0309994 Document Type C - Proceedings Paper (int. conf.) R&D Document Type Conference Paper Title Metalation of 6-halo-2,4-dimethoxypyrimidines as the key step for the synthesis of biologicaly active compounds Title Metalace 6-halo-2,4-dimethoxypyrimidinů jako klíčový krok pro syntézu biologicky aktivních sloučenin Author(s) Nencka, Radim (UOCHB-X) RID, ORCID
Hřebabecký, Hubert (UOCHB-X) RID, ORCID
Votruba, Ivan (UOCHB-X) RID
Dračínský, Martin (UOCHB-X) RID, ORCID
Holý, Antonín (UOCHB-X)Source Title Chemistry of Nucleic Acid Components. - Praha : Institute of Organic Chemistry and Biochemistry ASCR, 2008 / Hocek Michal - ISBN 978-80-86241-29-6 Pages s. 249-253 Number of pages 5 s. Action Symposium on Chemistry of Nucleic Acid Components /14./ Event date 08.06.2008-13.06.2008 VEvent location Český Krumlov Country CZ - Czech Republic Event type EUR Language eng - English Country CZ - Czech Republic Keywords pyrimidine ; organometallic ; cross-coupling ; lithiation Subject RIV CC - Organic Chemistry R&D Projects 1M0508 GA MŠMT - Ministry of Education, Youth and Sports (MEYS) 1QS400550501 GA AV ČR - Academy of Sciences of the Czech Republic (AV ČR) CEZ AV0Z40550506 - UOCHB-X (2005-2011) UT WOS 000257885700042 Annotation Introduction of carbon substituents to the position C-5 and C-6 of uracil ring was performed by reaction of organometallic derivatives of uracil with electrophiles or by transition metal catalyzed cross-coupling reaction. Especially lithiathion was studied intensively. Workplace Institute of Organic Chemistry and Biochemistry Contact asep@uochb.cas.cz ; Kateřina Šperková, Tel.: 232 002 584 ; Jana Procházková, Tel.: 220 183 418 Year of Publishing 2009
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