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Pharmacokinetics and distribution of I-125-PLA-b-PEO block copolymers in rats

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    0189112 - UMCH-V 20033066 RIV US eng J - Journal Article
    Nováková, K. - Lázníček, M. - Rypáček, František - Machová, Luďka
    Pharmacokinetics and distribution of I-125-PLA-b-PEO block copolymers in rats.
    Pharmaceutical Development and Technology. Roč. 8, č. 2 (2003), s. 153-161. ISSN 1083-7450. E-ISSN 1097-9867
    R&D Projects: GA MŠMT LN00B125; GA MŠMT LN00A065; GA AV ČR IAA4050202; GA AV ČR KSK4055109
    Institutional research plan: CEZ:AV0Z4050913
    Keywords : block * copolymers * drug delivery
    Subject RIV: CC - Organic Chemistry
    Impact factor: 0.657, year: 2003

    The PLA-b-PEO block copolymers were studied as potential carriers for anti-inflammatory and anticancer drugs. The study indicates that PLA-b-PEO copolymers, having different molecular weight of the chains, have similar biological behavior in most organs and tissues.
    Permanent Link: http://hdl.handle.net/11104/0084958

     
     

Number of the records: 1  

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