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Investigation of novel Mn(ıı) fenamato complexes with neocuproine and their effects on endometrial cell lines
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SYSNO ASEP 0574225 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve WOS Title Investigation of novel Mn(ıı) fenamato complexes with neocuproine and their effects on endometrial cell lines Author(s) Klepcová, Z. (SK)
Špaková, I. (SK)
Madreiter-Sokolowski, C.T. (AT)
Graier, W. (AT)
Kalinová, K. (SK)
Samoľová, Erika (FZU-D) ORCID
Smolková, R. (SK)
Smolko, L. (SK)
Rabajdová, M. (SK)Number of authors 9 Source Title New Journal of Chemistry. - : Royal Society of Chemistry - ISSN 1144-0546
Roč. 47, č. 28 (2023), s. 13088-13097Number of pages 10 s. Language eng - English Country GB - United Kingdom Keywords Mn(ıı) complexes ; neocuproine ; crystal structure ; x-ray diffraction ; cytotoxic effect Subject RIV BM - Solid Matter Physics ; Magnetism OECD category Condensed matter physics (including formerly solid state physics, supercond.) R&D Projects LM2018096 GA MŠMT - Ministry of Education, Youth and Sports (MEYS) Method of publishing Limited access Institutional support FZU-D - RVO:68378271 UT WOS 000994203000001 EID SCOPUS 85160424294 DOI 10.1039/d3nj00412k Annotation Two novel Mn(ıı) complexes with non-steroidal anti-inflammatory drugs, fenamic (Hfen = 2-(phenylamino) benzoic acid) and flufenamic acid (Hflu = N-(3-trifluoromethylphenyl)-2-aminobenzoic acid) and neocuproine (neo) as a supporting ligand were designed, synthesized and characterized. Their molecular structure was determined by the single-crystal X-ray diffraction method. The cytotoxic effects of the complexes were studied on three selected cell lines, including epithelial hTERT HME1 used as a healthy control, endometriotic 12Z and endometrial cancer SK-UT-1. Workplace Institute of Physics Contact Kristina Potocká, potocka@fzu.cz, Tel.: 220 318 579 Year of Publishing 2024 Electronic address https://doi.org/10.1039/d3nj00412k
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