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Cancer cells use self-inflicted DNA breaks to evade growth limits imposed by genotoxic stress

  1. 1.
    SYSNO0557631
    TitleCancer cells use self-inflicted DNA breaks to evade growth limits imposed by genotoxic stress
    Author(s) Larsen, B. (DK)
    Benada, J. (DK)
    Yung, P. (SE)
    Bell, R. (CA)
    Pappas, G. (DK)
    Urban, Václav (UMG-J) [37]
    Ahlskog, J. (DK)
    Kuo, T. (DK)
    Janščák, Pavel (UMG-J) [44] RID
    Megeney, L. (CA)
    Elsaesser, S. (SE)
    Bártek, Jiří (UMG-J) [37] RID
    Sorensen, C.S. (DK)
    Corespondence/seniorSorensen, C.S. - Korespondující autor
    Source Title Science. Roč. 376, č. 6592 (2022), s. 476-483. - : American Association for the Advancement of Science
    Document TypeČlánek v odborném periodiku
    Grant GA19-07674S GA ČR - Czech Science Foundation (CSF)
    Institutional supportUMG-J - RVO:68378050
    Languageeng
    CountryUS
    Keywords caspase-activated dnase * cycle checkpoint * gene-expression * strand breaks * genome * inhibition * damage * death * phosphorylation * differentiation
    Cooperating institutions Univ Copenhagen, Biotech Res & Innovat Ctr, DK-2200 Copenhagen N, Denmark
    Karolinska Inst, Dept Med Biochem & Biophys, Div Genome Biol, Sci Life Lab, S-17165 Stockholm, Sweden
    Univ Ottawa, Ottawa Hosp Res Inst, Sprott Ctr Stem Cell Res, Ottawa, ON K1H 8L6, Canada
    Univ Ottawa, Dept Med, Ottawa, ON K1H 8L6, Canada
    Univ Ottawa, Dept Cellular & Mol Med, Ottawa, ON K1H 8L6, Canada
    Danish Canc Soc Res Ctr, DK-2100 Copenhagen, Denmark
    Acad Sci Czech Republ, Inst Mol Genet, Prague 14300, Czech Republic
    Univ Zurich, Inst Mol Canc Res, CH-8057 Zurich, Switzerland
    URLhttps://www.science.org/doi/10.1126/science.abi6378
    Permanent Linkhttp://hdl.handle.net/11104/0331729
     
Number of the records: 1  

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