Number of the records: 1  

Formation of gadolinium-ferritin from clinical magnetic resonance contrast agents

  1. 1.
    SYSNO ASEP0537034
    Document TypeJ - Journal Article
    R&D Document TypeJournal Article
    Subsidiary JČlánek ve WOS
    TitleFormation of gadolinium-ferritin from clinical magnetic resonance contrast agents
    Author(s) Neburková, Jitka (UOCHB-X) RID, ORCID
    Rulseh, A. M. (CZ)
    Chang, S. L. Y. (AU)
    Raabová, Helena (UOCHB-X)
    Vejpravová, J. (CZ)
    Dračínský, Martin (UOCHB-X) RID, ORCID
    Tarábek, Ján (UOCHB-X) RID, ORCID
    Kotek, J. (CZ)
    Pingle, M. (CZ)
    Majer, Pavel (UOCHB-X)
    Vymazal, J. (CZ)
    Cígler, Petr (UOCHB-X) RID, ORCID
    Source TitleNanoscale Advances. - : Royal Society of Chemistry - ISSN 2516-0230
    Roč. 2, č. 12 (2020), s. 5567-5571
    Number of pages5 s.
    Languageeng - English
    CountryGB - United Kingdom
    Keywordsnephrogenic systemic fibrosis ; high signal intensity ; dentate nucleus
    Subject RIVCD - Macromolecular Chemistry
    OECD categoryNano-materials (production and properties)
    R&D ProjectsEF16_019/0000729 GA MŠMT - Ministry of Education, Youth and Sports (MEYS)
    Method of publishingOpen access
    Institutional supportUOCHB-X - RVO:61388963
    UT WOS000599127600006
    EID SCOPUS85097958025
    DOI10.1039/c9na00567f
    AnnotationGadolinium deposition in the brain following administration of gadolinium-based contrast agents (GBCAs) has led to health concerns. We show that some clinical GBCAs form Gd3+-ferritin nanoparticles at (sub)nanomolar concentrations of Gd3+ under physiological conditions. We describe their structure at atomic resolution and discuss potential relevance for clinical MRI.
    WorkplaceInstitute of Organic Chemistry and Biochemistry
    Contactasep@uochb.cas.cz ; Kateřina Šperková, Tel.: 232 002 584 ; Jana Procházková, Tel.: 220 183 418
    Year of Publishing2021
    Electronic addresshttps://doi.org/10.1039/C9NA00567F
Number of the records: 1  

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