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Surface plasmon resonance biosensor for the ultrasensitive detection of bisphenol A
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SYSNO ASEP 0507808 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve WOS Title Surface plasmon resonance biosensor for the ultrasensitive detection of bisphenol A Author(s) Chadtová Song, Xue (URE-Y)
Gedeonová, Erika (URE-Y)
Homola, Jiří (URE-Y) RIDNumber of authors 3 Source Title Analytical and Bioanalytical Chemistry. - : Springer - ISSN 1618-2642
Roč. 411, č. 22 (2019), s. 5655-5658Number of pages 4 s. Publication form Print - P Language eng - English Country DE - Germany Keywords Surface plasmon resonance biosensor ; Bisphenol A ; Functionalized gold nanoparticles Subject RIV CB - Analytical Chemistry, Separation OECD category Analytical chemistry R&D Projects NV16-27611A GA MZd - Ministry of Health (MZ) Method of publishing Limited access Institutional support URE-Y - RVO:67985882 UT WOS 000482452600005 EID SCOPUS 85068326553 DOI 10.1007/s00216-019-01996-8 Annotation Bisphenol A (BpA) is a chemical that is extensively used in common plastic products, such as food and drink containers. It can leach from the plastics and penetrate into the human body, where it acts as an endocrine disruptor with significant risks to human health. In order to minimize the exposure of human populations to BpA, methods for the detection of BpA are needed. In this work, we present a novel surface plasmon resonance (SPR) biosensor for ultrasensitive detection of BpA. Our approach combines a binding inhibition assay with functionalized gold nanoparticles for the enhancement of sensor response. We demonstrate that the developed biosensor enables the detection of BpA in a wide range of concentrations (0.01 to 100,000 ng/mL) with an extremely low limit of detection—5.2 pg/mL. Workplace Institute of Radio Engineering and Electronics Contact Petr Vacek, vacek@ufe.cz, Tel.: 266 773 413, 266 773 438, 266 773 488 Year of Publishing 2020 Electronic address https://link.springer.com/article/10.1007%2Fs00216-019-01996-8
Number of the records: 1