Recent strategies toward microfluidic-based surface-enhanced Raman spectroscopy

0480525 - ÚIACH 2018 RIV DE eng J - Journal Article
Týčová, Anna - Přikryl, Jan - Foret, František
Recent strategies toward microfluidic-based surface-enhanced Raman spectroscopy.
Electrophoresis. Roč. 38, č. 16 (2017), s. 1977-1987. ISSN 0173-0835. E-ISSN 1522-2683
R&D Projects: GA ČR(CZ) GBP206/12/G014
Grant - others:AV ČR(CZ) MSM200311601
Program: Program na podporu mezinárodní spolupráce začínajících výzkumných pracovníků
Institutional support: RVO:68081715
Keywords : microfluidics * nanoparticles * separation * Surface-enhanced Raman spectroscopy
OECD category: Analytical chemistry
Impact factor: 2.569, year: 2017

Surface-enhanced Raman spectroscopy (SERS) is an extremely powerful analytical tool, which not only yields information about the molecular structure of the analyte in the form of characteristic vibrational spectrum but also gives sensitivities approaching those in fluorescence spectroscopy. The SERS measurement on the microfluidic platform provides possibility to manufacture the device with design perfectly fulfilling the needs of the application with minimal sample consumption. This review aims at describing basic strategies for SERS measurement in microfluidic devices published in the last decade and covers current trends in microfluidics with SERS detection in the field of bioanalysis and approaches toward on-line coupling of liquid-based separation techniques with SERS detection.
Permanent Link: http://hdl.handle.net/11104/0276293