Cell-compatible conducting polyaniline films prepared in colloidal dispersion mode

0475208 - ÚMCH 2018 RIV NL eng J - Journal Article
Kašpárková, V. - Humpolíček, P. - Capáková, Z. - Bober, Patrycja - Stejskal, Jaroslav - Trchová, Miroslava - Rejmontová, P. - Junkar, I. - Lehocký, M. - Mozetič, M.
Cell-compatible conducting polyaniline films prepared in colloidal dispersion mode.
Colloids and Surfaces B-Biointerfaces. Roč. 157, 1 September (2017), s. 309-316. ISSN 0927-7765. E-ISSN 1873-4367
R&D Projects: GA ČR(CZ) GA17-05095S
Institutional support: RVO:61389013
Keywords : polyaniline * conducting films * colloidal dispersions
OECD category: Polymer science
Impact factor: 3.997, year: 2017

Conducting polyaniline can be prepared and modified using several procedures, all of which can significantly influence its applicability in different fields of biomedicine or biotechnology. The modifications of surface properties are crucial with respect to the possible applications of this polymer in tissue engineering or as biosensors. Innovative technique for preparing polyaniline films via in-situ polymerization in colloidal dispersion mode using four stabilizers (poly-N-vinylpyrrolidone, sodium dodecylsulfate, Tween 20 and Pluronic F108) was developed. The surface energy, conductivity, spectroscopic features, and cell compatibility of thin polyaniline films were determined using contact-angle measurement, the van der Pauw method, Fourier-transform infrared spectroscopy, and assay conducted on mouse fibroblasts, respectively. The stabilizers significantly influenced not only the surface and electrical properties of the films but also their cell compatibility. Sodium dodecylsulfate seems preferentially to combine both the high conductivity and good cell compatibility. Moreover, the films with sodium dodecylsulfate were non-irritant for skin, which was confirmed by their in-vitro exposure to the 3D-reconstructed human tissue model.
Permanent Link: http://hdl.handle.net/11104/0272191