Bacteria isolated from bats skin as source of antifungal compounds with activity against the white nose syndrome agent pseudogymnoascus destructans

0465448 - MBÚ 2017 ES eng A - Abstract
García Fraile, Paula - Badouchová, H. - Kohoutová, L. - Pikula, J. - Kolařík, Miroslav
Bacteria isolated from bats skin as source of antifungal compounds with activity against the white nose syndrome agent pseudogymnoascus destructans.
New Biotechnology. Barcelona: European Federation of Biotechnology, 2016. s. 417-417. ISSN 1871-6784. E-ISSN 1876-4347
Institutional support: RVO:61388971
Keywords : antifungal compounds * white nose syndrom * pseudogymnoascus destructans

Most bat species are listed in the IUCN Red list of endangered species. White-nose syndrome (WNS) has killed thousands of bats in North America. The ascomycete Pseudogymnoascus destructans (formerly known as Geomyces destructans) has been reported as responsible of the WNS. Moreover, bats carry different bacteria of unknown pathogenic importance which may help in the preservation of this endangered group of mammals. In this work we isolated several bacterial strains from bats skin swabs onto blood agar plates. The strains were identified by 16S rRNA sequencing and tested for their ability to inhibit P. destructans
by using double cultures assays. We found several bacterial strains classified in the genera Pseudomonas, Serratia, Providencia and Acinetobacter showing different grades of fungal growth inhibition. Finally, strains producing larger fungal inhibition halos were selected for antifungal compounds extraction and further analysis.

Permanent Link: http://hdl.handle.net/11104/0264308