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Function of thin film nanocrystalline diamond-protein SGFET independent of grain size
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SYSNO ASEP 0386606 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve WOS Title Function of thin film nanocrystalline diamond-protein SGFET independent of grain size Author(s) Krátká, Marie (FZU-D) RID, ORCID
Kromka, Alexander (FZU-D) RID, ORCID, SAI
Ukraintsev, Egor (FZU-D) RID, ORCID
Ledinský, Martin (FZU-D) RID, ORCID, SAI
Brož, A. (CZ)
Kalbáčová, M. (CZ)
Rezek, Bohuslav (FZU-D) RID, ORCIDSource Title Sensors and Actuators B - Chemical. - : Elsevier - ISSN 0925-4005
166-167, May (2012), s. 239-245Number of pages 7 s. Language eng - English Country CH - Switzerland Keywords nanocrystalline diamond ; solution-gated field-effect transistors (SGFETs) ; fetal bovine serum ; osteoblastic cells Subject RIV BM - Solid Matter Physics ; Magnetism R&D Projects GD202/09/H041 GA ČR - Czech Science Foundation (CSF) GBP108/12/G108 GA ČR - Czech Science Foundation (CSF) GAP108/12/0996 GA ČR - Czech Science Foundation (CSF) KAN400100701 GA AV ČR - Academy of Sciences of the Czech Republic (AV ČR) CEZ AV0Z10100521 - FZU-D (2005-2011) UT WOS 000305356900035 DOI https://doi.org/10.1016/j.snb.2012.02.049 Annotation We employ nanocrystalline diamond (NCD) thin films with average grain sizes of 250 and 80 nm to resolve influence of grain boundaries and sp2 phase on protein adsorption and electronic function of solutiongated field-effect transistors (SGFET). Microscopic (20 u m × 60 um) SGFETs are fabricated without gate oxides based on hydrogen-terminated NCD films on glass substrates. We show that NCD with grain sizes down to 80 nm and film thickness of 100 nm is fully operational as SGFET. We find that inherent hysteresis of SGFET transfer characteristics, their reaction time, their negative shift after protein adsorption and cell culturing process, low gate leakage currents and no influence of UV sterilization or rinsing are all independent of the NCD grain size. Thus we propose a microscopic model where the function of NCD SGFET is determined by the H-terminated surface of diamond nanocrystals and its interaction with proteins, not by grain boundaries or sp2 phase in general. Workplace Institute of Physics Contact Kristina Potocká, potocka@fzu.cz, Tel.: 220 318 579 Year of Publishing 2013
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