Number of the records: 1
A simple drug anchoring microfiber scaffold for chondrocyte seeding and proliferation
- 1.0377778 - ÚEM 2013 RIV GB eng J - Journal Article
Rampichová, Michala - Martinová, L. - Košťáková, E. - Filová, Eva - Míčková, Andrea - Buzgo, Matej - Michálek, Jiří - Přádný, Martin - Nečas, A. - Lukáš, D. - Amler, Evžen
A simple drug anchoring microfiber scaffold for chondrocyte seeding and proliferation.
Journal of Materials Science-Materials in Medicine. Roč. 23, č. 2 (2012), s. 555-563. ISSN 0957-4530. E-ISSN 1573-4838
R&D Projects: GA MŠMT 2B06130; GA AV ČR(CZ) IAA500390702
Grant - others:GA MŠk(CZ) ME10145; GA MZd(CZ) NT12156; GA MŠk(CZ) GA UK 122508; GA MŠk(CZ) 1M0510; GA ČR(CZ) GA202/09/1151
Program: 1M; GA
Institutional research plan: CEZ:AV0Z50390512; CEZ:AV0Z50390703; CEZ:AV0Z40500505
Institutional support: RVO:68378041 ; RVO:61389013
Keywords : Osteochondral defect * Articular cartilage * 2-hydroxyethyl methacrylate
Subject RIV: FP - Other Medical Disciplines; FP - Other Medical Disciplines (UMCH-V)
Impact factor: 2.141, year: 2012
Microfiber meshes made from poly(2-hydroxyethyl methacrylate) (PHEMA) showed promise as scaffolds for chondrocyte seeding and proliferation. Moreover, the peak liposome adhesion to PHEMA microfiber scaffolds observed in our study resulted in the development of a simple drug anchoring system. Attached foetal bovine serum-loaded liposomes significantly improved both chondrocyte adhesion and proliferation.
Permanent Link: http://hdl.handle.net/11104/0209848
Number of the records: 1