High-resolution biosensor based on localized surface plasmons

0374560 - ÚFE 2013 RIV US eng J - Journal Article
Piliarik, Marek - Šípová, Hana - Kvasnička, Pavel - Galler, N. - Krenn, J. R. - Homola, Jiří
High-resolution biosensor based on localized surface plasmons.
Optics Express. Roč. 20, č. 1 (2012), s. 672-680. ISSN 1094-4087
R&D Projects: GA AV ČR KAN200670701; GA MŠMT OC09058
Institutional research plan: CEZ:AV0Z20670512
Keywords : optical biosenzor * surface plasmon resonance * localized surface plasmon
Subject RIV: JA - Electronics ; Optoelectronics, Electrical Engineering
Impact factor: 3.546, year: 2012

We report on a new biosensor with localized surface plasmons (LSP) based on an array of gold nanorods and TIR imaging in polarization contrast. The sensitivity of the new biosensor is characterized and a model detection of DNA hybridization is carried out and results compared with a conventional SPR biosensor, showing the same performance while involving significantly lower surface densities of interacting molecules. Limit of detection was 100 pM and a surface density resolution only 35 fg×mm2.
Permanent Link: http://hdl.handle.net/11104/0216253