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Novel isopolar non-isosteric phosphonate analogues of 3´-deoxy-3´,4´-didehydronucleoside 5´-phosphates
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SYSNO ASEP 0353427 Document Type C - Proceedings Paper (int. conf.) R&D Document Type The record was not marked in the RIV Title Novel isopolar non-isosteric phosphonate analogues of 3´-deoxy-3´,4´-didehydronucleoside 5´-phosphates Author(s) Petrová, Magdalena (UOCHB-X) RID
Buděšínský, Miloš (UOCHB-X) RID, ORCID
Rosenberg, Ivan (UOCHB-X) RID, ORCIDNumber of authors 3 Source Title International Roundtable on Nucleosides, Nucleotides and Nucleic Acids. IRT 2010. - Lyon : Université de Lyon, 2010 Pages s. 311-312 Number of pages 2 s. Action International Roundtable on Nucleosides, Nucleotides and Nucleic Acids. IRT 2010 Event date 29.08.2010-03.09.2010 VEvent location Lyon Country FR - France Event type EUR Language eng - English Country FR - France Keywords phosphonate analog ; triphosphate analog ; didehydronucleoside Subject RIV CC - Organic Chemistry R&D Projects LC06077 GA MŠMT - Ministry of Education, Youth and Sports (MEYS) LC06061 GA MŠMT - Ministry of Education, Youth and Sports (MEYS) GA202/09/0193 GA ČR - Czech Science Foundation (CSF) CEZ AV0Z40550506 - UOCHB-X (2005-2011) Annotation Isopolar non-isosteric phosphonate analogue of 3´-deoxy-3´,4´-didehydronucleoside 5´-phosphates was prepared and converted to diphosphoryl derivative. The obtained 5´-triphosphate analogue was checked as substrate for HCV RNA-dependent RNA polymerase. Workplace Institute of Organic Chemistry and Biochemistry Contact asep@uochb.cas.cz ; Kateřina Šperková, Tel.: 232 002 584 ; Jana Procházková, Tel.: 220 183 418 Year of Publishing 2011
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