Covalent labeling of RNA with VI- valent osmium complexes

Number of the records: 1

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SYSNO ASEP	0309369
Document Type	A - Abstract
R&D Document Type	The record was not marked in the RIV
R&D Document Type	Není vybrán druh dokumentu
Title	Covalent labeling of RNA with VI- valent osmium complexes
Title	Kovalentní značení RNA komplexy šestimocného osmia
Author(s)	Trefulka, Mojmír (BFU-R)_{RID, ORCID} Paleček, Emil (BFU-R)_{RID, ORCID}
Source Title	Book of Abstracts. - Brno, 2008 S. 65
Number of pages	1 s.
Action	Electrochemistry of Nucleic Acids and Proteins - New Tools for Biotechnologies (Satellite Symposium to ESEAC 2008 Prague)
Event date	19.06.2008-22.06.2008
VEvent location	Brno
Country	CZ - Czech Republic
Event type	CST
Language	eng - English
Country	CZ - Czech Republic
Keywords	modification of RNA ; six valent osmium complexes ; electroactive labels
Subject RIV	BO - Biophysics
R&D Projects	GA301/07/0490 GA ČR - Czech Science Foundation (CSF)
	KAN400310651 GA AV ČR - Academy of Sciences of the Czech Republic (AV ČR)
CEZ	AV0Z50040507 - BFU-R (2005-2011)
	AV0Z50040702 - BFU-R (2007-2013)
Annotation	Six valent osmium ligand complexes [Os(VI)L] react with 1,2-diol groups and potential target of modification are mono- and poly-saccharide molecules, glycoproteins and 3' ends of oligoribonucleotides. We showed that electroactive label can be introduced in the nucleoside and nucleotide ribose residues using six-valent osmium complexes.
Workplace	Institute of Biophysics
Contact	Jana Poláková, polakova@ibp.cz, Tel.: 541 517 244
Year of Publishing	2009

Number of the records: 1