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Detection of DNA hybridization using a new type of electrochemical sensor
- 1.0309221 - BFÚ 2009 CA eng A - Abstract
Jelen, František - Lesnikowski, Z. - Ojelniczak, A. - Kouřilová, Alena - Hasoň, Stanislav - Paleček, Emil
Detection of DNA hybridization using a new type of electrochemical sensor.
[Detekce DNA hybridizace založená na novém typu elektrochemické značky.]
Conference Program and Abstract Booklet. Vancouver, 2008. s. 187.
[7th International Conference on the Scientific and Clinical Applications of Magnetic Carriers. 20.05.2008-24.05.2008, Vancouver]
R&D Projects: GA AV ČR(CZ) IAA100040602; GA AV ČR(CZ) IAA400040804
Institutional research plan: CEZ:AV0Z50040507; CEZ:AV0Z50040702
Keywords : DNA hybridization * electrochemical sensor * carborane cluster
Subject RIV: BO - Biophysics
Electrochemical detection of DNA hybridization connected with paramagnetic beads and a carbon paste electrode was presented. We have found that carborane cluster bound to oligonucleotide chain can be used as a suitable electrochemical redox label of DNA hybridization.
Byla presentována elektrochemická detekce DNA hybridizace spojená s použitím magnetických kuliček a uhlíkové pastové elektrody. Bylo zjištěno, že karboranové klastery navázané na oligonukleotid mohou být využity jako vhodná redoxní značka pro detekci DNA hybridizace.
Permanent Link: http://hdl.handle.net/11104/0161427
Number of the records: 1