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The simulation of effect of membrane channel block by propafenone on electrical activity on human atrial cells
- 1.0211711 - UT-L 20000269 RIV CZ eng C - Conference Paper (international conference)
Brožková, K. - Pásek, Michal - Šlichta, J.
The simulation of effect of membrane channel block by propafenone on electrical activity on human atrial cells.
Biomechanics of man 2000. Olomouc: Palackého univerzita, 2000 - (Vaverka, F.; Janura, M.), s. 139-140. ISBN 80-244-0193-2.
[Conference of the Czech Society of biomechanics with international participation Biomechanics of man 2000. Olomouc (CZ), 24.11.2000-25.11.2000]
Institutional research plan: CEZ:AV0Z2076919
Keywords : quantitative modelling * propafenone * cardiac cells
Subject RIV: CE - Biochemistry
The main aim of this study is to explore the effect of propafenone on suppression of irregular excitations in human atrial cell. A program was designed that contains the computational model of electric activity on human atrial cells and the mathematical model of interaction of propafenone with INa-channels. This integrated model can served for simulations of the drug effects.
Permanent Link: http://hdl.handle.net/11104/0107260
Number of the records: 1