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Synthesis of linear comb-like tetrameric peptide and glycopeptide dendrimers with Tn antigen

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    0194904 - UOCHB-X 20030212 RIV GB eng C - Conference Paper (international conference)
    Vepřek, Pavel - Knytlová, K. - Hajdúch, M. - Trnka, T. - Sejbal, J. - Ježek, Jan
    Synthesis of linear comb-like tetrameric peptide and glycopeptide dendrimers with Tn antigen.
    Innovation and Perspectives in Solid Phase Synthesis & Combinatorial Libraries. Kingswinford: Mayflower Worldwide Ltd, 2003 - (Epton, R.), s. 267-270. ISBN 0-9515735-4-3.
    [Inovation and Perspectives in Solid Phase Synthesis & Combinatorial Libraries. Southampton (GB), 18.09.2001-22.09.2001]
    R&D Projects: GA ČR GA303/01/0690
    Institutional research plan: CEZ:AV0Z4055905
    Keywords : glycopeptide dendrimers * Tn antigen
    Subject RIV: CC - Organic Chemistry

    Glycopeptide antigen bearing only B-cell epitope and glycopeptide antigen bearing both B- and T-cell epitopes (Tn dimer, triglycine spacer and PKYVKQNTLKLAT (307-319) sequence derived from .I.Influenza virus hemagglutinin./I.) (IV) and their non-glycosylated analogues (I and III) were synthesized manually in syringes by Fmoc/tBu chemistry.
    Permanent Link: http://hdl.handle.net/11104/0090574

     
     

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