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DNA adducts, p53 and p21WAF1 espression, and cell cycl alterations after exposure of embryonal human lung fibroblasts to PAHs

  1. 1.
    SYSNO ASEP0173365
    Document TypeC - Proceedings Paper (int. conf.)
    R&D Document TypeConference Paper
    TitleDNA adducts, p53 and p21WAF1 espression, and cell cycl alterations after exposure of embryonal human lung fibroblasts to PAHs
    Author(s) Giguere, Y. (XX)
    Binková, Blanka (UEM-P)
    Rössner ml., Pavel (UEM-P) RID, ORCID
    Dostál, Miroslav (UEM-P) RID
    Šrám, Radim (UEM-P) RID
    Source TitleProceedings of the 30th Annual Meeting of European Environmental Mutagen Society. - Budapest : EEMS, 2000
    Pagess. p150
    Number of pages1 s.
    ActionAnnual Meeting of EEMS /30./
    Event date22.08.2000-26.08.2000
    VEvent locationBudapest
    CountryHU - Hungary
    Languageeng - English
    CountryHU - Hungary
    Subject RIVDN - Health Impact of the Environment Quality
    R&D ProjectsSI/340/2/00 GA MŽP - Ministry of Environment (MŽP)
    CEZAV0Z5039906 - UEM-P
    AnnotationThe effect of exposure to dibenzo[a,l]pyrene and benzo[a]pyrene in human diploid lung fibroblast cells was studied in an in vitro system using multiple end-points: DNA adduct levels were measured by 32P-postlabelling, the expression of p53 and p21 prooteins by western blotting and the cell cycle distribution by flow cytometry.
    WorkplaceInstitute of Experimental Medicine
    ContactLenka Koželská, lenka.kozelska@iem.cas.cz, Tel.: 241 062 218, 296 442 218
    Year of Publishing2001

Number of the records: 1  

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