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Effect of increased pressure loading on heart growth in neonatal rats
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SYSNO ASEP 0142450 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Ostatní články Title Effect of increased pressure loading on heart growth in neonatal rats Author(s) Sedmera, D. (CH)
Thompson, R. P. (US)
Kolář, František (FGU-C) RID, ORCID, SAISource Title Journal of Molecular and Cellular Cardiology. - : Elsevier - ISSN 0022-2828
Roč. 35, č. 3 (2003), s. 301-309Number of pages 9 s. Language eng - English Country GB - United Kingdom Keywords aortic constriction ; cardiomyocyte proliferation ; hypertrophy Subject RIV ED - Physiology R&D Projects GA305/01/0279 GA ČR - Czech Science Foundation (CSF) LN00A069 GA MŠMT - Ministry of Education, Youth and Sports (MEYS) CEZ AV0Z5011922 - FGU-C Annotation We studied the growth response of the rat left ventricle to pressure overload induced by aortic constriction at postnatal day 2. The results suggest that adaptation of the neonatal myocardium to increased load is rapid, and is based on transitory hyperplasia followed by hypertrophy of myocytes. Workplace Institute of Physiology Contact Lucie Trajhanová, lucie.trajhanova@fgu.cas.cz, Tel.: 241 062 400 Year of Publishing 2004
Number of the records: 1