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Development of the inner ear in Splotch mutant mice
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SYSNO ASEP 0109646 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Ostatní články Title Development of the inner ear in Splotch mutant mice Title Vývoj vnitřního ucha u mutantních myší Splotch Author(s) Buckiová, Daniela (UEM-P)
Syka, Josef (UEM-P) RIDSource Title Neuroreport - ISSN 0959-4965
Roč. 15, č. 13 (2004), s. 2001-2005Number of pages 5 s. Language eng - English Country US - United States Keywords inner ear ; Pax-3 Subject RIV FF - HEENT, Dentistry R&D Projects GA309/04/1074 GA ČR - Czech Science Foundation (CSF) NR8113 GA MZd - Ministry of Health (MZ) CEZ AV0Z5039906 - UEM-P Annotation We show that the homozygous Splotch mutation (Sp(2H)) is associated with severe defects that prevent the formation of the cochlea and vestibulo-cochlear ganglion.During the period of vestibular and cochlear ganglia formation, PSA NCAM expression was decreased. The expression of calcium binding proteins (S100) in the vestibulo-cochlear ganglion was also decreased Workplace Institute of Experimental Medicine Contact Lenka Koželská, lenka.kozelska@iem.cas.cz, Tel.: 241 062 218, 296 442 218 Year of Publishing 2005
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