Number of the records: 1

Compounds for inhibition of fibroblast activation protein

SYSNO ASEP	0581089
Document Type	P - Patent
R&D Document Type	Patent or other outcome protected by special legislation
Title	Compounds for inhibition of fibroblast activation protein
Author(s)	Šimková, Adéla (UOCHB-X)_{ORCID, RID} Šácha, Pavel (UOCHB-X)_{RID, ORCID} Sidej, Natan (UOCHB-X)_ORCID Ormsby, Tereza (UOCHB-X)_{ORCID, RID} Konvalinka, Jan (UOCHB-X)_{RID, ORCID}
Year of issue	2023
Possible third party use of the result	A - Pro využití výsledku jiným subjektem je vždy nutné nabytí licence
Royalty requested	A - Poskytovatel licence požaduje licenční poplatek
Patent no. or utility model no. or industrial design no.	AU2021248368
Date of the patent acceptance	06.04.2023
Name of the patent owner	Ústav organické chemie a biochemie AV ČR, v. v. i
Code of the issuer name	AU001 - IP Australia Phillip ACT
Current use	A - Pouze udělený (dosud nevyužívaný) patent nebo patent využívaný jeho vlastníkem
Territorial Protection	NEU - národní patent v zemi mimo EU PCT - mezinárodní patentová ochrana dle Smlouvy o patentové spolupráci
Language	eng - English
Keywords	FAP ; protease ; inhibition
OECD category	Medicinal chemistry
R&D Projects	GA19-10280S GA ČR - Czech Science Foundation (CSF)
	NV15-31379A GA MZd - Ministry of Health (MZ)
	EF16_019/0000729 GA MŠMT - Ministry of Education, Youth and Sports (MEYS)
	LM2015064 GA MŠMT - Ministry of Education, Youth and Sports (MEYS)
	NU22-03-00318 GA MZd - Ministry of Health (MZ)
	LX22NPO5102 GA MŠMT - Ministry of Education, Youth and Sports (MEYS)
Institutional support	UOCHB-X - RVO:61388963
Annotation	This invention provides quinolinecarboxamide compounds of general formula I which by far exceed the previously known FAP inhibitors in affinity and inhibitory effect. These agents can be used to specifically target tumours for diagnostic and therapeutic purposes, or for laboratory purposes in the study of endogenous FAP expression.
Workplace	Institute of Organic Chemistry and Biochemistry
Contact	asep@uochb.cas.cz ; Kateřina Šperková, Tel.: 232 002 584 ; Jana Procházková, Tel.: 220 183 418
Year of Publishing	2024
Electronic address	https://worldwide.espacenet.com/patent/search/family/075953813/publication/AU2021248368B2?q=AU2021248368B2

Number of the records: 1