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LDL-C augments whereas HDL-C prevents inflammatory innate immune memory
- 1.0569082 - ÚMG 2023 RIV GB eng J - Journal Article
Sohrabi, Yahya - Schwarz, D. - Reinecke, H.
LDL-C augments whereas HDL-C prevents inflammatory innate immune memory.
Trends in Molecular Medicine. Roč. 28, č. 1 (2022), s. 1-4. ISSN 1471-4914. E-ISSN 1471-499X
Institutional support: RVO:68378050
Keywords : atheroslerosis * lipoproteins * cholesterol * inflammation * innate immunity * cardiometabolic diseases
OECD category: Biochemistry and molecular biology
Impact factor: 13.6, year: 2022
Method of publishing: Open access
https://www.sciencedirect.com/science/article/pii/S1471491421003002?via%3Dihub
Recent studies emphasize the importance of low-density lipoprotein cholesterol (LDL-C) in altering the hematopoietic cell compartment of bone marrow and of high-density inhibiting metabolic endotoxemia-induced inflammation. The data suggest that these lipoproteins may exert their inflammatory or anti-inflammatory roles by modulating innate immune memory. HDL-C subfractions could therefore potentially reduce the residual risk in hepatic and cardiometabolic disease.
Permanent Link: https://hdl.handle.net/11104/0340388
Number of the records: 1