Discovery of a New Isoxazole-3-hydroxamate-Based Histone Deacetylase 6 Inhibitor SS-208 with Antitumor Activity in Syngeneic Melanoma Mouse Models

Shen, S., Hadley, M., Ustinova, K., Pavlíček, J., Knox, T., Noonepalle, S., Tavares, M. T., Zimprich, C. A., Zhang, A., Robers, M. B., Bařinka, C., Kozikowski, A. P., Villagra, A. Discovery of a New Isoxazole-3-hydroxamate-Based Histone Deacetylase 6 Inhibitor SS-208 with Antitumor Activity in Syngeneic Melanoma Mouse Models. Journal of Medicinal Chemistry. 2019, 62(18), 8557-8577. ISSN 0022-2623. E-ISSN 1520-4804. Available: doi: 10.1021/acs.jmedchem.9b00946.